The Aldolase A (2C9) Monoclonal Antibody from Bioss Inc. is a Rabbit Monoclonal antibody to ALDOA. This antibody recognizes Human, Mouse, Rat, and Zebrafish/Fish antigen. The Aldolase A (2C9) Monoclonal Antibody has been validated for the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. In addition, may also function as a scaffolding protein. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10